NKH 477 hydrochloride
CAS No. 138605-00-2
NKH 477 hydrochloride ( Colforsin dapropate )
Catalog No. M11605 CAS No. 138605-00-2
NKH 477 hydrochloride (Colforsin dapropate) is a water-soluble analog of Forskolin and a potent activator of adenylyl cyclase.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
100MG | Get Quote | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameNKH 477 hydrochloride
-
NoteResearch use only, not for human use.
-
Brief DescriptionNKH 477 hydrochloride (Colforsin dapropate) is a water-soluble analog of Forskolin and a potent activator of adenylyl cyclase.
-
DescriptionNKH 477 hydrochloride (Colforsin dapropate) is a water-soluble analog of Forskolin and a potent activator of adenylyl cyclase, shows some selectivity for cardiac (type V) adenylyl cyclase; increases cAMP accumulation in HEK293 cells stably overexpressing type V more than forskolin; A PKA activator.Heart Failure Approveed
-
SynonymsColforsin dapropate
-
PathwayMetabolic Enzyme/Protease
-
TargetAdenylate Cyclase
-
RecptorAdenylate Cyclase
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number138605-00-2
-
Formula Weight546.10
-
Molecular FormulaC27H43NO8.HCl
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCC(C)CCC(O[C@@H]([C@@]1([H])C(C)(C)CC[C@H](O)[C@@]12C)[C@H](OC(C)=O)[C@]3(C)[C@]2(O)C(C[C@](C)(C=C)O3)=O)=O.[H]Cl
-
Chemical Name(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-β-alanine, N,N-dimethyl-oxo-1H-naphtho[2,1-b]pyran-6-yl ester hydrochloride
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Hosono M, et al. J Cardiovasc Pharmacol. 1992 Apr;19(4):625-34.
2. Toya Y, et al. J Mol Cell Cardiol. 1998 Jan;30(1):97-108.
2. Toya Y, et al. J Mol Cell Cardiol. 1998 Jan;30(1):97-108.
molnova catalog
related products
-
TIP 39, Tuberoinfund...
This is a tuberoinfundibular neuropeptide and parathyroid hormone 2(PTH 2)-receptor agonist from hypothalmus. Synthetic TIP39 activates human and rat PTH2 receptors.
-
LRE1
A novel potent, specific and allosteric soluble adenylyl cyclase (sAC) inhibitor with IC50 of 3.3 uM in RF-MSS assays.
-
Small Cardioactive P...
Small Cardioactive Peptide B (SCPB), a neurally active peptide, stimulates adenylate cyclase activity in particulate fractions of both heart and gill tissues with EC50s of 0.1 and 1.0 μM, respectively.